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Catalog Number | orb1805495 |
---|---|
Category | Antibodies |
Description | Anti-TSLP Reference Antibody is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa. |
Clonality | Monoclonal |
Tested applications | ELISA, FA, FACS, Kinetics |
Reactivity | Human |
Isotype | IgG |
Purity | > 95% |
Conjugation | Unconjugated |
MW | 145.5 kDa |
Target | TSLP |
Endotoxins | < 1 EU/mg |
Storage | -80°C |
Buffer/Preservatives | 100 mM Pro-Ac 20 mM Arg pH 5.0 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Anti-TSLP Reference Antibody (tezepelumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-TSLP Reference Antibody (tezepelumab)is more than 98.64% ;determined by SEC-HPLC.
Immobilized human TSLP His at 2 μg/mL can bind Anti-TSLP Reference Antibody (tezepelumab);EC50=0.0518μg/mL.
Anti-TSLP Reference Antibody (tezepelumab)-induced FACS Blocking activity was evaluated using TSLPR/IL7R-CHO-K. The IC50 was approximately 0.0802 μg/mL.
Tezepelumab reduced levels of IL13 in BALF of OVA asthma model on B-hTSLP/hTSLPR mice. The result showed significant IL13 inhibition effects at 15 mpk.
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, Kinetics | |
Human, Monkey | |
Monoclonal | |
Unconjugated |
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