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Item 1 of 2
Anti-Hu LOX1 Purified
Catalog Number: orb1467380
| Catalog Number | orb1467380 |
|---|---|
| Category | Antibodies |
| Description | LOX1, a 31 kDa type II transmembrane protein, is a C-type lectin, functioning as a scavenger receptor for e.g. oxidized low density lipoprotein, apoptotic heat shock proteins, or CRP. It is expressed by macrophages, fibroblasts, platelets, endothelial cells, and smooth muscle cells, and its defects can lead to atherosclerosis. Its expression is enhanced under inflammatory conditions. Multiple splicing variants have been identified. |
| Clonality | Monoclonal |
| Clone Number | 15C4 |
| Tested applications | FC, ICC, IHC-Fr |
| Reactivity | Human |
| Isotype | Mouse IgG2a kappa |
| Immunogen | fusion protein of human LOX1 ectodomain and of human IgG Fc |
| Antibody Type | Primary Antibody |
| Concentration | 1 mg/ml |
| Purity | Purified by protein-A affinity chromatography. |
| Conjugation | Unconjugated |
| Target | LOX1 |
| Hazard Information | Non-Toxic |
| Entrez | 4973 |
| UniProt ID | P78380 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | OLR1, SLOX1, SCARE1, CLEC8A Read more... |
| Note | For research use only |
| Application notes | Flow cytometry: Recommended dilution: 1-5 µg/ml |
| Expiration Date | 12 months from date of receipt. |
Separation of human dendritic cells (red-filled) from human lymphocytes (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human LOX1 (15C4) purified antibody (concentration in sample 5 μg/ml, GAM APC).
Flow cytometry surface staining pattern of human dendritic cells in flow cytometry analysis (surface staining) stained using anti-human LOX1 (15C4) purified antibody (concentration in sample 5 μg/ml, GAM APC).
