LOX-1 Rabbit Polyclonal Antibody

SKU: orb6324

Description

LOX-1 Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes LOX-1. Generated against a KLH conjugated synthetic peptide derived from human LOX-1. The peptide is available as orb374785. The suitable applications for this antibody are ELISA, ICC, IF, IHC-P and WB.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: ELISA, ICC, IF, IHC-P, WB
• Dilution Range: IF/ICC: 1:100, WB: 2 μg/ml, IHC-P: 1:200

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human LOX-1. Please contact us for the exact immunogen sequence. The peptide is available as orb374785.
• Target: LOX-1
• Molecular Weight: 31 kDa
• Purity: Polyclonal antibodies are purified by peptide affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 10 mM PBS, 0.02% sodium azide
• Concentration: - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-CLEC8A antibody, anti-hLOX 1 antibody, anti-hLOX-1 antibody, anti-Lectin like oxidized LDL receptor 1 antibody, anti-Lectin like oxLDL receptor 1 antibody, anti-Lectin type oxidized LDL receptor 1 antibody, anti-Lectin-like oxidized LDL receptor 1 antibody, anti-Lectin-like oxLDL receptor 1 antibody, anti-Lectin-type oxidized LDL receptor 1 antibody, anti-low density lipoprotein oxidized, receptor 1 antibody, anti-LOX-1 antibody, anti-LOX 1 antibody, anti-LOX1 antibody, anti-LOXIN antibody, anti-Olr1 antibody, anti-OLR1_HUMAN antibody, anti-Ox LDL receptor 1 antibody, anti-Ox-LDL receptor 1 antibody, anti-Oxidized low density lipoprotein receptor 1 antibody, anti-SCARE1 antibody, anti-Scavenger receptor class E, member 1 antibody, anti-SLOX1 antibody, anti-SR-EI antibody

IHC-P of human lung carcinoma tissue using LOX-1 antibody (diluton at 1:200)

Immunohistochemical staining of mouse lung tissue using LOX-1 antibody (dilution of primary antibody - 1:100)

IHC-P image of pig stomach tissue using anti-LOX-1 (dilution of primary antibody at 1:100)

IHC-P image of mouse lung tissue using LOX-1 antibody (dilution of primary antibody at 1:100)

IHC-P staining of pig stomach tissue using anti-LOX-1 (dilution at 1:100)

Immunofluorescence analysis of rat brain tissue using LOX-1 antibody (dilution of primary antibody - 1:100)

Immunofluorescence image of rat brain tissue using anti-LOX-1 (dilution at 1:100)

Western blot analysis of rat lung tissue using LOX-1 antibody (dilution at: 2 ug/ml)

Immunohistochemical staining of rat brain tissue using LOX-1 antibody (dilution of primary antibody - 1:100)

Quick Database Links

Gene Symbol

LOX-1

UniProt

P78380, Q9EQ09, O70156

NCBI Gene ID

4973

RefSeq:001166103, 11, 001172632

Xinhua Li, Xuejun Wang, Zhouyang Hu, Zhaoxiong Chen, Haoxi Li, Xiaoming Liu, Zhi Yao Yong, Shanjing Wang, Zhanying Wei, Yingchao Han, Jun Tan, Cong Li, Xiao bo He, Guixin Sun, Desheng Wu, Lijun Li Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation Scientific Reports, 7, 7403 (2017)

PubMed: 28785062

Applications

IHC

Reactivity

Human

Chang, Kuan-Cheng et al. Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction J Mol Cell Cardiol, 84, 36-44 (2015)

PubMed: 25871829