CD11b Antibody

SKU: orb154428

Description

Mouse monoclonal antibody to CD11b

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: FA, FC, ICC, IHC-Fr, IP
• Reactivity: Human, Primate
• Application Notes:
  Functional application: Blocking of granulocyte activation. Flow cytometry: Recommended dilution: 1-12 µg/ml

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: ICRF44
• Immunogen: Rheumatoid synovial cells and human monocytes.
• Target: CD11b
• Purification: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mac-1, Integrin alpha M, ITGAM, CR3A, MO1A, MAC1A

Separation of human neutrophil granulocytes (red-filled) from CD11b negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD11b (ICRF44) purified antibody (low endotoxin, concentration in sample 6 μg/ml) GAM APC.

Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD11b (ICRF44) purified antibody (low endotoxin, concentration in sample 6 μg/ml) GAM APC.

Quick Database Links

Gene Symbol

CD11b

UniProt

P11215

NCBI Gene ID

3684