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Ac4ManNAz
Catalog Number: orb1220165
| Catalog Number | orb1220165 |
|---|---|
| Category | Small Molecules |
| Description | Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
| Target | PEGs |
| Purity | >98% (HPLC) |
| MW | 430.4 |
| CAS Number | 361154-30-5 |
| Formula | C₁₆H₂₂N₄O₁₀ |
| Storage | Storage temperature: -20°C. Stability: ≥ 2 years |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Ac4ManNAz [orb532361]
mass identification (ESI-MS)
361154-30-5
Theoretical MW: 430.37 g/mol; Detected MW: 430.13 g/mol
C16H22N4O10
100 mgAc4ManNAz [orb1308698]
98.42%
361154-30-5
430.37
C16H22N4O10
2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)Ac4ManNAz [orb1734948]
mass identification (ESI-MS)
361154-30-5
Theoretical MW: 430.37 g/mol; Detected MW: 430.13 g/mol
C16H22N4O10
5 mgAc4ManNAz [orb1734949]
mass identification (ESI-MS)
361154-30-5
Theoretical MW: 430.37 g/mol; Detected MW: 430.13 g/mol
C16H22N4O10
5 x 5 mg
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
