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8-OH-Dpat

SKU: orb1690004

Description

8-Hydroxy-DPAT (8-OH-DPAT) is a selective serotonin 1A (5-HT1A) receptor agonist widely used in neuroscience research. It is employed in both in vitro binding assays and in vivo studies to investigate serotonin's role in behaviors like anxiety, depression, and locomotion.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number78950-78-4
MW247.38
Purity95.96% (May vary between batches)
FormulaC16H25NO
SMILESCCCN(CCC)C1CCc2cccc(O)c2C1
Target5-HT Receptor
SolubilityDMSO:49 mg/mL (198.08 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.08 mM)

Bioactivity

Target IC50
5-HT1A:8.19 (pIC50)|5-HT7 receptor:466 nM (Ki)

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

8 OH Dpat, 8OHDpat, 8-OH-Dpat, 8-Hydroxy-DPAT, 5-HT1A, 5-HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, 5-HT7, inhibit, Inhibitor, Serotonin Receptor

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

8-OH-Dpat (orb1690004)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 230.00
DispatchUsually dispatched within 3-5 working days
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