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8-OH-Dpat

SKU: orb1690004

Description

8-Hydroxy-DPAT (8-OH-DPAT) is a selective serotonin 1A (5-HT1A) receptor agonist widely used in neuroscience research. It is employed in both in vitro binding assays and in vivo studies to investigate serotonin's role in behaviors like anxiety, depression, and locomotion.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number78950-78-4
MW247.38
Purity99.38% (May vary between batches)
FormulaC16H25NO
SMILESCCCN(CCC)C1CCc2cccc(O)c2C1
Target5-HT Receptor
SolubilityDMSO:49 mg/mL (198.08 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.08 mM)

Bioactivity

Target IC50
5-HT1A:8.19 (pIC50)|5-HT7 receptor:466 nM (Ki)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

8 OH Dpat, 8OHDpat, 8-OH-Dpat, 8-Hydroxy-DPAT, 5-HT1A, 5-HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, 5-HT7, inhibit, Inhibitor, Serotonin Receptor

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 100.00
25 mg
$ 160.00