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Escholtzine

SKU: orb3179509

Description

Escholtzine is an alkaloid found in the California poppy (Eschscholzia californica). It inhibits the binding of [3H]8-OH-DPAT to 5-HT1A receptors with an EC50 of 11 μM and a Ki of 6 μM. Escholtzine also inhibits CYP3A4, displaying an IC50 of 13.4 μg/mL. It is utilized in research concerning neurological disorders such as anxiety.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number4040-75-9
MW323.35
FormulaC19H17NO4
SMILESCN1[C@@]2(C=3C(C[C@]1(C=4C(C2)=CC5=C(C4)OCO5)[H])=CC6=C(C3)OCO6)[H]
TargetCytochromes P450,5-HT Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information