10-Deacetyltaxol

SKU: orb1302036

Description

10-Deacetyltaxol (10-DAT) is a natural taxane derivative isolated from the bark of the Pacific yew, Taxus brevifolia. It serves as a key biosynthetic precursor in paclitaxel research and is used in vitro to study structure-activity relationships and microtubule stabilization mechanisms.

Research Area

Signal Transduction

Key Properties

• CAS Number: 78432-77-6
• MW: 811.87
• Purity: 99.93% (May vary between batches)
• Formula: C₄₅H₄₉NO₁₃
• SMILES: CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C([C@@H](O)C1=O)C2(C)C
• Target: Microtubule Associated
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.16 mM);DMSO:27.5 mg/mL (33.87 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, inhibit, Inhibitor, Deacetyl Paclitaxel, Deacetyltaxol, 10-DAT, 10 Deacetyltaxol, 10-Desacetyl Paclitaxel, 10Deacetyltaxol, 10-Deacetyltaxol, 10-Deacetylpaclitaxel, 10-deacetyl-paclitaxel

Compound Identifiers

PubChem CID

155831