Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

YHO-13177

SKU: orb1302725

Description

YHO-13177 is a potent and selective BCRP inhibitor that enhances SN-38 cytotoxicity in vitro. It shows no activity against P-glycoprotein, as demonstrated in MDR1-transduced K562 cell models. This compound is a valuable research tool for investigating BCRP-mediated drug resistance in cancer.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number912287-56-0
MW370.47
Purity98.78% (May vary between batches)
FormulaC20H22N2O3S
SMILESCOc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N
TargetBCRP
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.4 mM);DMSO:45 mg/mL (121.47 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

YHO 13177, YHO13177, YHO-13177, BCRP, ABCG2, Breast cancer resistance protein, Inhibitor, inhibit

Similar Products

  • YHO-13351 free base [orb1708203]

    >99.99% (May vary between batches)

    912288-64-3

    483.62

    C26H33N3O4S

    1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 ml x 10 mM (in DMSO)
  • YHO-13177 [orb1223674]

    >98% (HPLC)

    912287-56-0

    370.4653

    C20H22N2O3S

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 130.00
10 mg
$ 160.00
25 mg
$ 270.00
50 mg
$ 380.00
100 mg
$ 590.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry