Cart summary

You have no items in your shopping cart.

YHO-13177

SKU: orb1302725

Description

YHO-13177 is a potent and selective BCRP inhibitor that enhances SN-38 cytotoxicity in vitro. It shows no activity against P-glycoprotein, as demonstrated in MDR1-transduced K562 cell models. This compound is a valuable research tool for investigating BCRP-mediated drug resistance in cancer.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number912287-56-0
MW370.47
Purity98.78% (May vary between batches)
FormulaC20H22N2O3S
SMILESCOc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N
TargetBCRP
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.4 mM);DMSO:45 mg/mL (121.47 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

YHO 13177, YHO13177, YHO-13177, BCRP, ABCG2, Breast cancer resistance protein, Inhibitor, inhibit

Similar Products

  • YHO-13351 free base [orb1708203]

    >99.99% (May vary between batches)

    912288-64-3

    483.62

    C26H33N3O4S

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 mg, 1 ml x 10 mM (in DMSO)
  • YHO-13177 [orb1223674]

    >98% (HPLC)

    912287-56-0

    370.5

    C20H22N2O3S

    50 mg, 5 mg, 10 mg, 25 mg, 100 mg, 1 g, 500 mg, 200 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

YHO-13177 (orb1302725)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 130.00
10 mg
$ 160.00
25 mg
$ 270.00
50 mg
$ 380.00
100 mg
$ 590.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry