yangonin

SKU: orb1303412

Description

Yangonin is a novel ligand for the human recombinant cannabinoid (CB) receptor. Its affinity for this target makes it a candidate for investigating NF-κB-driven pathologies, including inflammation, in both cellular and animal models of disease.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 500-62-9
• MW: 258.27
• Purity: 99.55% (May vary between batches)
• Formula: C₁₅H₁₄O₄
• SMILES: COc1ccc(\C=C\c2cc(OC)cc(=O)o2)cc1
• Target: Autophagy,Cannabinoid Receptor,NF-κB
• Solubility: DMSO:10 mg/mL (38.72 mM)

Bioactivity

• Target IC50:
  CB1:1.79 ± 0.53 μM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, Nuclear factor-kappaB, Nuclear factor-κB, NF-kB, NFkB, NF-κB, NFκB, inhibit, CB1, CB, Cannabinoid Receptor, CannabinoidReceptor, Autophagy, Y-100550, Y100550, yangonin, Y 100550

Compound Identifiers

PubChem CID

5281575