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Catalog Number | orb1301325 |
---|---|
Category | Small Molecules |
Description | Desmethoxyyangonin |
CAS Number | 15345-89-8 |
Purity | 99.61% |
MW | 228.24 |
SMILES | COc1cc(\C=C\c2ccccc2)oc(=O)c1 |
Formula | C14H12O3 |
Biological Activity | 1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |