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WRN inhibitor 2

SKU: orb2278145

Description

WRN Inhibitor 2 (example 118) is a potent small molecule targeting the Werner syndrome helicase, with a pIC50 ≥ 7.0. This inhibitor is a valuable research tool for studying DNA repair mechanisms and microsatellite instability in cancer models, both in vitro and in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Images & Validation

Key Properties

CAS Number2923009-56-5
MW420.38
FormulaC15H11F3N2O5S2
SMILESOC1=C(C=2C=C(C(F)(F)F)SC2)NC(=O)C(C(N[C@@H]3C=CS(=O)(=O)C3)=O)=C1
TargetDNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information