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Wnt pathway inhibitor 5

SKU: orb2944959

Description

Compound 28 (Wntpathway inhibitor 5) is a potent small molecule Wnt pathway inhibitor with sub-nanomolar activity (IC50 < 0.003 µM). It is utilized in cancer research, demonstrating efficacy in vitro and in vivo against models including breast cancer, osteosarcoma, and head and neck squamous cell carcinoma.

Research Area

Signal Transduction, Stem Cell & Developmental Biology, Stem Cell & Developmental Biology; Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1385817-77-5
MW439.459
FormulaC26H19F2N5
SMILESFC1=NC=CC(=C1)C=2C=CC(=CC2F)CNC3=NC=CC=4C=C(N=CC43)C=5C=CN=C(C5)C
TargetWnt/beta-catenin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information