iCRT-5

SKU: orb1700367

Description

iCRT-5 is a potent small molecule Wnt/β-catenin pathway inhibitor with demonstrated antiproliferative and pro-apoptotic activity. It is a valuable research tool for studying Wnt-driven pathologies, including multiple myeloma, in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 18623-44-4
• MW: 367.44
• Purity: 99.68%
• Formula: C₁₆H₁₇NO₅S₂
• SMILES: COc1ccc(\C=C2/SC(=S)N(CCCC(O)=O)C2=O)cc1OC
• Target: Apoptosis,Wnt/beta-catenin
• Solubility: DMSO:30 mg/mL (81.65 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

iCRT 5, iCRT5, iCRT-5, betacatenin, beta-catenin, Apoptosis, bcatenin, Wnt/β-catenin, Wnt, Wnt/betacatenin, Wnt/b-catenin, βcatenin

Compound Identifiers

PubChem CID

1416325