Xanthatin

SKU: orb1303437

Description

Xanthatin is a bioactive small molecule with cytotoxic, antibacterial (including against MRSA), and antifungal properties. Research indicates potential therapeutic applications in non-small cell lung cancer (NSCLC) and melanoma, where it inhibits proliferation and angiogenesis, potentially via modulation of the Wnt/β-catenin pathway.

Research Area

Cardiovascular Research, Cell Biology, Infectious Disease & Virology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 26791-73-1
• MW: 246.3
• Purity: 99.96% (May vary between batches)
• Formula: C₁₅H₁₈O₃
• SMILES: [H][C@]12C[C@H](C)C(\C=C\C(C)=O)=CC[C@]1([H])C(=C)C(=O)O2
• Target: Apoptosis,Wnt/beta-catenin,Antibacterial,Lipoxygenase,VEGFR
• Solubility: DMSO:65 mg/mL (263.91 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble

Bioactivity

• Target IC50:
  T. b. brucei:2.63 µg/mL (IC50)|VEGFR2:3.8 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LOX, Lipoxygenase, inhibit, parasite, Inhibitor, breast, beta-catenin, betacatenin, cancer, bcatenin, Apoptosis, antiinflammatory, Bacterial, 5-lipoxygenase, Wnt/b-catenin, Wnt/β-catenin, Wnt/betacatenin, Wnt, Xanthatin, T. b. brucei, Vascular endothelial growth factor receptor, VEGFR, βcatenin

Compound Identifiers

PubChem CID

5281511