Wnt pathway activator 1

SKU: orb1307606

Description

Wnt pathway activator 1 is a highly potent small molecule Wnt/β-catenin signaling agonist, exhibiting an IC50 of 28-29 nM. It is utilized in research exploring hair follicle regeneration and has shown potential in preclinical models for androgenetic alopecia. This compound is a valuable tool for both in vitro and in vivo studies of Wnt pathway biology.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1360540-81-3
• MW: 296.32
• Purity: 99.94% (May vary between batches)
• Formula: C₁₈H₁₆O₄
• SMILES: O=C(CCC(=O)c1ccc2OCCOc2c1)c1ccccc1
• Target: Wnt/beta-catenin
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (8.44 mM);DMSO:60 mg/mL (202.48 mM)

Bioactivity

• Target IC50:
  Wnt:28-29 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

beta-catenin, betacatenin, bcatenin, inhibit, Inhibitor, βcatenin, Wnt/β-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt pathway activator 1, Wnt pathway activator1, Wnt pathway activator-1

Compound Identifiers

PubChem CID

56837361