Val-Cit

SKU: orb1307264

Description

Val-Cit is a protease-cleavable dipeptide linker widely used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy. Its application is critical in both in vitro biochemical assays and in vivo preclinical studies to develop novel therapeutics.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 159858-33-0
• MW: 274.32
• Purity: 99.74% (May vary between batches)
• Formula: C₁₁H₂₂N₄O₄
• SMILES: [C@H](NC([C@H](C(C)C)N)=O)(CCCNC(N)=O)C(O)=O
• Target: ADC Linker,PROTAC Linker

Bioactivity

• In Vitro:
  ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Cleavable, Antibody-drug conjugates linkers, ADC Linker, ADCLinker, ADC Linkers, ValCit, Val-Cit, Val Cit

Compound Identifiers

PubChem CID

9921644