Boc-Val-Cit-PAB

SKU: orb1307483

Description

Boc-Val-Cit-PAB is a protease-cleavable linker used in the construction of antibody-drug conjugates (ADCs) for targeted cancer therapy. It enables the controlled release of cytotoxic payloads in both in vitro and in vivo research models, facilitating the study of ADC efficacy and stability.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 870487-09-5
• MW: 479.57
• Purity: 99.22% (May vary between batches)
• Formula: C₂₃H₃₇N₅O₆
• SMILES: CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
• Target: ADC Linker,PROTAC Linker
• Solubility: DMSO:10 mM

Bioactivity

• In Vitro:
  ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADC Linkers, ADCLinker, ADC Linker, Antibody-drug conjugates linkers, Boc Val Cit PAB, BocValCitPAB, Boc-Val-Cit-PAB, Cleavable, Inhibitor, inhibit

Compound Identifiers

PubChem CID

59841854