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Boc-Val-Cit-PAB

SKU: orb1307483

Description

Boc-Val-Cit-PAB is a protease-cleavable linker used in the construction of antibody-drug conjugates (ADCs) for targeted cancer therapy. It enables the controlled release of cytotoxic payloads in both in vitro and in vivo research models, facilitating the study of ADC efficacy and stability.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number870487-09-5
MW479.57
Purity99.34% (May vary between batches)
FormulaC23H37N5O6
SMILESO=C(NCCC[C@H](NC([C@@H](NC(OC(C)(C)C)=O)C(C)C)=O)C(NC1=CC=C(CO)C=C1)=O)N
TargetADC Linker,PROTAC Linker
SolubilityDMSO:10 mM

Bioactivity

In Vitro
ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ADC Linkers, ADCLinker, ADC Linker, Antibody-drug conjugates linkers, Boc Val Cit PAB, BocValCitPAB, Boc-Val-Cit-PAB, Cleavable, Inhibitor, inhibit

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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50 mg
$ 80.00
100 mg
$ 90.00
DispatchUsually dispatched within 5-10 working days
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