FMoc-Val-Cit-PAB-PNP

SKU: orb1299526

Description

Fmoc-Val-Cit-PAB-PNP is a protease-cleavable linker used in the construction of antibody-drug conjugates (ADCs) for targeted cancer therapy research. It enables the controlled release of cytotoxic payloads in both in vitro and in vivo experimental models, facilitating the study of ADC efficacy and stability.

Key Properties

• CAS Number: 863971-53-3
• MW: 766.8
• Purity: 98.46% (May vary between batches)
• Formula: C₄₀H₄₂N₆O₁₀
• SMILES: O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O)=O)=O
• Target: ADC Linker
• Solubility: DMSO:247.5 mg/mL (322.77 mM);10% DMSO+90% Corn Oil:4 mg/mL (5.22 mM)

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibody-drug conjugates linkers, ADCLinker, ADC Linkers, ADC Linker, inhibit, FMocValCitPABPNP, FMoc-Val-Cit-PAB-PNP, FMoc Val Cit PAB PNP, Inhibitor

Compound Identifiers

PubChem CID

57641184