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TRPM4-IN-2

SKU: orb1688762

Description

TRPM4-IN-2 (NBA) is a potent TRPM4 channel inhibitor with an IC50 of 0.16 µM. It is a useful research tool for studying TRPM4's role in prostate and colorectal cancer models, both in vitro and in vivo.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number667411-04-3
MW355.77
Purity>99.99% (May vary between batches)
FormulaC19H14ClNO4
SMILESO(CC(NC1=C(C(O)=O)C=CC(Cl)=C1)=O)C=2C3=C(C=CC2)C=CC=C3
TargetTRP/TRPV Channel
SolubilityDMSO:90 mg/mL (252.97 mM)

Bioactivity

Target IC50
TRPM4:0.16 μM
In Vitro
TRPM4-IN-2 (NBA) at a concentration of 50 μM blocked 88 ± 9% of endogenous TRPM4 currents within 500 seconds.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NBA, TRP Channel, TRPChannel, TRPM4, TRPM4-IN-2, TRPV Channel, TRPVChannel

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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100 mg
$ 1,110.00
250 mg
$ 1,810.00
1 g
$ 3,580.00
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