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NMDAR/TRPM4-IN-2

SKU: orb2280004

Description

NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.

Images & Validation

Key Properties

CAS Number2243506-33-2
MW293.631021022797
Purity>98%
FormulaC11H18BRCLN2
SMILESC(C1C=CC=C(Br)C=1)N(CC)CCN.Cl

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • NMDAR/TRPM4-IN-2 [orb1744757]

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    2243506-33-2

    330.092

    C11H19BrCl2N2

    5 mg, 100 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg
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NMDAR/TRPM4-IN-2 (orb2280004)

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100 mg
$ 700.00
250 mg
$ 1,140.00
1 g
$ 2,250.00
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