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Topoisomerase I inhibitor 2

SKU: orb1689410

Description

Topoisomerase I inhibitor 2 (ZML-8) is a selective Top1 inhibitor that induces DNA damage, leading to G2/M phase arrest and apoptosis. Its anti-tumor activity has been demonstrated in both in vitro cell-based assays and in vivo xenograft models, supporting its use in cancer research.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

CAS Number2588211-44-1
MW293.32
FormulaC18H15NO3
SMILESO(C)C=1C=C2C=C3C=4C(OCC3=NC2=CC1OC)=CC=CC4
TargetCaspase,Topoisomerase,Others,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information