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(±)-10-Hydroxycamptothecin

SKU: orb1308344

Description

(±)-10-Hydroxycamptothecin is a natural alkaloid derived from Camptotheca acuminata that acts as a selective inhibitor of DNA topoisomerase I. It serves as a key research compound for studying anticancer mechanisms and has been used in both in vitro cytotoxicity assays and in vivo tumor model studies to evaluate its therapeutic potential.

Research Area

Molecular Biology

Images & Validation

Key Properties

CAS Number64439-81-2
MW364.35
FormulaC20H16N2O5
SMILESCCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
TargetTopoisomerase
SolubilityDMSO:29.71 mg/mL (81.54 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Topoisomerase, Topo I, Inhibitor, Hydroxy Camptothecine, inhibit, (±) 10 Hydroxycamptothecin, (±)10Hydroxycamptothecin, 10-Hydroxycamptothecin

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 80.00
25 mg
$ 100.00
50 mg
$ 130.00
100 mg
$ 160.00
500 mg
$ 330.00
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