HAVCR2 Antibody

SKU: orb1410433

Description

Mouse monoclonal antibody to TIM3

Research Area

Cardiovascular Research, Immunology & Inflammation

Images & Validation

• Tested Applications: IHC, WB
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: TIM3/4027
• Immunogen: Recombinant fragment of human TIM3 protein (around aa 22-202) (exact sequence is proprietary)
• Target: HAVCR2
• Source/Expression System: Bioreactor
• Molecular Weight: 60kDa
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

CD366; HAVR2; Hepatitis A virus cellular receptor 2 (HAVCR2); Kidney injury molecule 3 (KIM3); T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIM3; TIMD3

Analysis of Protein Array containing more than 19000 full-length human proteins using TIM3-Monospecific Mouse Monoclonal Antibody (TIM3/4027). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human lymph node stained with TIM3 Mouse Monoclonal Antibody (TIM3/4027).

SDS-PAGE Analysis of Purified TIM3 Mouse Monoclonal Antibody (TIM3/4027). Confirmation of Integrity and Purity of Antibody.

Western blot analysis of human spleentissue lysate using Purified TIM3 Mouse Monoclonal Antibody (TIM3/4027).

Quick Database Links

Gene Symbol

HAVCR2

UniProt

Q8TDQ0