KCNK3 Antibody

SKU: orb151054

Description

Mouse Anti-Rat TASK-1 Potassium Channel Monoclonal IgG2b

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

• Tested Applications: ICC, IF, IHC, WB
• Dilution Range: WB (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml was sufficient for detection of TASK1 Potassium Channel in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: N374/48 (Formerly sold as S374-48)
• Immunogen: Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). < 30% identity with TASK3.
• Target: KCNK3
• Molecular Weight: 50kDa
• Purification: Protein G Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.1% sodium azide. Storage buffer changes when conjugated.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Potassium channel subfamily K member 3, KCNK3, Acid sensitive potassium channel protein TASK 1, Cardiac two pore background K(+) channel, cTBAK 1, K2p3.1, KCNK9, OAT1, rTASK, TASK 1, TBAK1, TWIK related acid sensitive K+ channel, Two pore potassium channel KT3.1, Two pore K(+) channel KT3.1

Quick Database Links

Gene Symbol

KCNK3

UniProt

O54912

NCBI Gene ID

29553

RefSeq (Protein):NP_203694.1