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Tacrine

SKU: orb1306361

Description

Tacrine is a centrally acting acetylcholinesterase inhibitor used as a cholinergic agonist in research. It is applied in studies of Alzheimer's disease, involving both in vitro enzyme assays and in vivo models to investigate cognitive enhancement and cholinergic mechanisms.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number321-64-2
MW198.26
Purity99.97% (May vary between batches)
FormulaC13H14N2
SMILESNc1c2CCCCc2nc2ccccc12
TargetAChR,Cholinesterase (ChE)
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.09 mM);H2O:Insoluble;DMSO:55 mg/mL (277.41 mM)

Bioactivity

Target IC50
AChE:109 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cholinergic, Cholinesterase (ChE), CS 12602, CS12602, CS-12602, Alzheimer's disease, hepatotoxicity, Inhibitor, inhibit, Tacrine, Tacrinum, Tetrahydroaminocrine

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Quality Guarantee

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Key Properties

No computed properties available.

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Tacrine (orb1306361)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 80.00
5 mg
$ 80.00
10 mg
$ 90.00
25 mg
$ 140.00
50 mg
$ 180.00
100 mg
$ 240.00
500 mg
$ 440.00
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