Tacrine hydrochloride (hydrate)

SKU: orb1306157

Description

Tacrine hydrochloride hydrate is a centrally-acting cholinesterase inhibitor used in research to study Alzheimer's disease and CNS disorders. It serves as a pharmacological tool in vitro and in vivo for investigating cholinergic neurotransmission, neuroprotection, and cognitive function.

Research Area

Neuroscience

Key Properties

• CAS Number: 206658-92-6
• MW: 252.74
• Purity: 99.89% (May vary between batches)
• Formula: C₁₃H₁₄N₂·XHCl·XH₂O
• SMILES: O.Cl.Nc1c2CCCCc2nc2ccccc12
• Target: Cholinesterase (ChE),AChR
• Solubility: H2O:252.2 mM;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL;DMSO:252.2 mM

Bioactivity

• Target IC50:
  BChE:25.6 nM|AChE:31 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tacrine, Tacrine HCI hydrate, Tacrine Hydrochloride, Tacrine hydrochloride (hydrate), Tacrine hydrochloride hydrate, AChR, AChE, Cholinesterase (ChE)

Compound Identifiers

PubChem CID

6420002