bis(7)-Tacrine

SKU: orb1704896

Description

Bis(7)-tacrine dihydrochloride is a dimeric derivative of tacrine that acts as a potent acetylcholinesterase (AChE) inhibitor, NMDA receptor blocker, and GABA A receptor antagonist. It has demonstrated neuroprotective effects against glutamate-induced apoptosis in vitro and shows potential for Alzheimer's disease research in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 224445-12-9
• MW: 565.63
• Formula: C₃₃H₄₂Cl₂N₄
• SMILES: Cl.Cl.C(CCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
• Target: iGluR,Others,GABA Receptor,Cholinesterase (ChE)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9959612