NR5A1 Antibody

SKU: orb1410307

Description

Mouse monoclonal antibody to Steroidogenic Factor 1 (Transcription Factor)

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: NR5A1/3420
• Immunogen: Recombinant fragment (around aa220-461) of human SF-1 protein
• Target: NR5A1
• Source/Expression System: Bioreactor
• Molecular Weight: 53kDa.
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Adrenal 4 binding protein (AD4BP); ELP; Fushi tarazu factor homolog 1 (FTZ1); Nuclear receptor AdBP4; Nuclear receptor subfamily 5 group A member 1 (NR5A1); POF7; SPGF8; SRXY3; Steroid hormone receptor Ad4BP; Steroidogenic factor 1 (SF1); Steroidogenic factor 1 nuclear receptor; STF1

Analysis of Protein Array containing >19000 full-length human proteins using Steroidogenic Factor 1 (SF-1) Mouse Monoclonal Antibody (NR5A1/3420). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human testis stained with SF-1 Mouse Monoclonal Antibody (NR5A1/3420) at 2 ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

Quick Database Links

Gene Symbol

NR5A1

UniProt

Q13285