SREBP1 (N) Antibody, Rabbit Polyclonal

SKU: orb66921

Description

Rabbit polyclonal to SREBP1.Sterol regulatory element-binding protein 1 (SREBP1) is a member of the basic helix-loop-helixleucinezipper (bHLH-Zip) transcription factor family, which is required for lipid homeostasis. SREBP1regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree thecholesterol synthesis pathway. SREBP1 binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'), and it has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').

Research Area

Metabolism Research

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human SREBP1
• Molecular Weight: 122
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-SREBP1 antibody,anti-Sterol regulatory elementbinding protein 1 antibody,anti-Class D basic helixloophelix protein 1 antibody,anti-bHLHd1 antibody,anti- Sterol regulatory elementbinding transcription factor 1 antibody,anti-SREBF1 antibody,anti-BHLHD1 antibody,anti-SREBP1 antibody

Quick Database Links

UniProt

P36956