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Catalog Number | orb67266 |
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Category | Antibodies |
Description | Rabbit polyclonal to SOCS6.Suppressor of cytokine signaling 6 (SOCS6) is a member of the SOCS family proteins that form partof a classical negative feedback system that regulates cytokine signal transduction. SOCS6 may be asubstrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomaldegradation of target proteins. SOCS6 regulates the degradation of the tyrosine-phosphorylated KITreceptor by ubiquitination. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse |
Immunogen | C-terminal region of human SOCS6 |
Dilution range | WB:1:500-1:2000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 60 |
UniProt ID | O14544 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-SOCS6 antibody,anti-Suppressor of cytokine si Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela(Lane1)
IF, IHC-Fr, IHC-P, WB | |
Rabbit | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF | |
Rabbit | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
PE/Cy5 |
IF | |
Rabbit | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
APC |
IF | |
Rabbit | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Cy3 |