SN-38 glucuronide

SKU: orb1983368

Description

SN-38 glucuronide is the inactive, detoxified metabolite of the topoisomerase I inhibitor Irinotecan. This derivative is a key research tool for studying the pharmacokinetics, toxicity, and reactivation mechanisms of Irinotecan in models of colorectal cancer, both in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 121080-63-5
• MW: 568.53
• Formula: C₂₈H₂₈N₂O₁₁
• SMILES: CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)cc12
• Target: Drug Metabolite,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

443154