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SIRT3 activator 2

SKU: orb2665458

Description

SIRT3 activator2 (compound 2a) is a direct-binding SIRT3 activator that promotes α-synuclein clearance in SH-SY5Y cells. It demonstrates neuroprotective effects in Parkinsonian mouse models, dose-dependently preserving dopaminergic neurons in the substantia nigra and improving motor function.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

CAS Number3061491-60-6
MW492.5
FormulaC22H24N2O9S
SMILESO=C(OCCCOC(CCN1C(C2(N3C(C(C)(C)C2)=O)CC1=O)=O)=O)C4=CC(S3(=O)=O)=CC=C4
TargetSirtuin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information