Silvestrol

SKU: orb1706633

Description

Silvestrol is a potent and selective inhibitor of eukaryotic initiation factor 4A (eIF4A), disrupting cap-dependent translation. This activity induces both autophagy and caspase-dependent apoptosis, making it a valuable tool for studying oncology, translational control, and cell death mechanisms in vitro and in vivo cancer models.

Research Area

Cell Biology

Key Properties

• CAS Number: 697235-38-4
• MW: 654.66
• Formula: C₃₄H₃₈O₁₃
• SMILES: CO[C@@H]1OC[C@@H](O[C@H]1Oc1cc2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)c2c(OC)c1)C(=O)OC)c1ccccc1)c1ccc(OC)cc1)[C@H](O)CO
• Target: PERK,Apoptosis,Autophagy,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11787114