Sheep anti Human Factor I

• Catalog Number: orb21240
• Category: Antibodies
• Description: Precipitating polyclonal sheep antiserum to human factor I. Factor I is a serine protease composed of two disulphide-linked chains. The protein has a molecular weight of 88.000 and its mean concentration in human plasma is 35 mg/ml. It is involved in the regulation of the C3/C5 convertase of either pathway. Using C4-binding protein or factor H splits the a chains of C4b or C3b respectively, which includes their roles in the C3/C5 convertases. It has been isolated as a homogenous protein for use in the antiserum production. Freund's complete adjuvant is used in the first step of the immunization procedure.
• Clonality: Polyclonal
• Species/Host: Sheep
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Delipidated, heat inactivated, lyophilized, stable IgG fraction. No preservative added. Total protein and IgG concentration are comparable to those of pooled normal sheep serum. No foreign proteins added.
• Buffer/Preservatives: Delipidated, heat inactivated, lyophilized, stable IgG fraction. No preservative added. Total protein and IgG concentration are comparable to those of pooled normal sheep serum. No foreign proteins added.
• UniProt ID: P05156
• RRID: AB_10752868
• Antibody Type: Primary Antibody
• Source: Factor I is a serine protease composed of two disulphide-linked chains. The protein has a molecular weight of 88.000 and its mean concentration in human plasma is 35 μg/ml. It is involved in the regulation of the C3/C5 convertase of either pathway. Using C4-binding protein or factor H splits the a chains of C4b or C3b respectively, which includes their roles in the C3/C5 convertases. It has been isolated as a homogenous protein for use in the antiserum production. Freund’s complete adjuvant is used in the first step of the immunization procedure.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Biorbyt accepts no liability for any inaccuracies or omissions in this information.
• Note: For research use only