SARS-CoV-2 (COVID-19) S1 Protein, His Tag

SKU: orb638775

Description

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Research Area

Infectious Disease & Virology

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.9 kDa. The protein migrates as 100-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	Spike S1
Reactivity	Virus
Tag	C-10×His
Molecular Weight	76.9 kDa
Expression Region	Val 16 - Arg 685
Purity	95%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

SARS-CoV-2 (2019-nCoV) S1 protein NTD, His Tag [orb689470]

Conjugation:	Unconjugated
Purity:	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 33.7 kDa after removal of the signal peptide. The apparent molecular mass of S1-NTD-His is approximately 55 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 10 μg, 100 μg, 50 μg

SARS-CoV-2 (COVID-19) S1 Protein NTD, His Tag [orb668899]
Conjugation:
Unconjugated
Purity:
90%
MW:
34.9 kDa
Sizes Available: 1 mg, 100 μg
SARS-CoV-2 (COVID-19) Omicron Variant Spike S1 (His-Avi Tag) Recombinant Protein [orb1228204]
Applications:
ELISA, SDS-PAGE, WB
Purity:
> 90% as determined by Bis-Tris PAGE
MW:
120 kD
Source:
HEK293 cells
Sizes Available: 0.05 mg

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Quick Database Links

Gene Symbol

Spike S1

UniProt

QHD43416.1

RefSeq:QHD43416.1

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	QHD43416.1

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