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Catalog Number | orb1824378 |
---|---|
Category | Antibodies |
Description | The family of EF-hand type Ca2+-binding proteins includes Calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 Alpha and beta, Calgranulins A (also designated MRP8), B (also designated MRP14) and C (S100A12, CGRP) and the parvalbumin family members, including parvalbumin Alpha and parvalbumin beta (also designated oncomodulin). Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 Alpha and beta are present in a variety of other tissues, and Calbindin is present in intestine and kidney. Parvalbumin Alpha is also found in fast-contracting/relaxing skeletal muscle fibers and parvalbumin beta is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Calgranulin is expressed in macrophages and epithelial cells. |
Species/Host | Rabbit |
Clonality | Recombinant |
Clone Number | S100A12/8952R |
Tested applications | IHC-P |
Reactivity | Human |
Isotype | Rabbit IgG, kappa |
Immunogen | A recombinant partial protein sequence (within amino acids 1-95) from the human protein was used as the immunogen for the CGRP antibody. |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This CGRP antibody is available for research use only. |
UniProt ID | P80511 |
Storage | Aliquot the CGRP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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