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RORγt Inverse agonist 3

RORγt Inverse agonist 3

Catalog Number: orb1708652

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Catalog Numberorb1708652
CategorySmall Molecules
DescriptionRORγt Inverse agonist 3
Purity98.00%
MW616.56
Biological ActivityRORγt Inverse agonist 3 is a potent, selective and orally active inverse agonist of RORγ(EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively).
CAS Number2364429-77-4
FormulaC29H31Cl2N5O4S
SMILESCNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)c(COc2cccc3c(cc(nc23)C(C)C)-c2cncn2C)c1Cl
Storage-20°C
NoteFor research use only
  • RORγt inverse agonist 13 [orb1297973]

    99.00%

    [2170477-75-3]

    513.29

    C23H17Cl2F3N2O4

    200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 1 mg, 1 ml x 10 mM (in DMSO)