Recombinant Aciculin Antibody / Phosphoglucomutase 5 / PGM5

• Catalog Number: orb2635748
• Category: Antibodies
• Description: Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
• Clonality: Recombinant
• Species/Host: Rabbit
• Isotype: Rabbit IgG, kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: Cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the recombinant Aciculin antibody.
• UniProt ID: Q15124
• Tested applications: IHC-P
• Dilution range: Immunohistochemistry (FFPE): 2-4ug/ml
• Application notes: Optimal dilution of the recombinant Aciculin antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: PGM5/7005R
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This recombinant Aciculin antibody is available for research use only.
• Note: For research use only

IHC staining of FFPE human prostate tissue with recombinant Aciculin antibody (clone PGM5/7005R) at 2 ug/ml. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free recombinant Aciculin antibody (clone PGM5/7005R) as confirmation of integrity and purity.