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Catalog Number | orb2635747 |
---|---|
Category | Antibodies |
Description | Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. |
Clonality | Recombinant |
Species/Host | Rabbit |
Isotype | Rabbit IgG, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the recombinant Aciculin antibody. |
UniProt ID | Q15124 |
Tested applications | IHC-P |
Dilution range | Immunohistochemistry (FFPE): 2-4ug/ml |
Application notes | Optimal dilution of the recombinant Aciculin antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | PGM5/7005R |
Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This recombinant Aciculin antibody is available for research use only. |
Note | For research use only |
IHC staining of FFPE human prostate tissue with recombinant Aciculin antibody (clone PGM5/7005R) at 2 ug/ml. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Aciculin antibody (clone PGM5/7005R) as confirmation of integrity and purity.
IHC-P | |
Human | |
Rabbit | |
Recombinant | |
Unconjugated |
IHC-P | |
Human | |
Rabbit | |
Recombinant | |
Unconjugated |