RANK Rabbit Polyclonal Antibody

SKU: orb6560

Description

RANK Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes RANK. Generated against a KLH conjugated synthetic peptide derived from human RANK. The peptide is available as orb393922. It is supplied in liquid form and exhibits reactivity with Human, Mouse and Rat samples. The suitable applications for this antibody are IHC-P.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: IHC-P
• Dilution Range: IHC-P: 1:100-1:500
• Reactivity: Human, Mouse, Rat

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human RANK. Please contact us for the exact immunogen sequence. The peptide is available as orb393922.
• Target: RANK
• Molecular Weight: 130kDa
• Purity: Purified by Protein A affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 10 mM PBS, 0.02% sodium azide
• Concentration: - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti CD254 antibody, anti hRANKL2 antibody, anti ODF antibody, anti OPGL antibody, anti Osteoclast differentiation factor antibody, anti Osteoprotegerin ligand antibody, anti Receptor activator of nuclear factor kappa B ligand antibody, anti Receptor activator of nuclear factor kappa-B ligand antibody, anti TNF related activation induced cytokine antibody, anti TNF-related activation-induced cytokine antibody, anti TNFSF 11 antibody, anti TNFSF11 antibody, anti TRANCE antibody, anti Tumor necrosis factor (ligand) superfamily member 11 antibody, anti Tumor necrosis factor ligand superfamily member 11 antibody, anti Tumor necrosis factor ligand superfamily member 11, soluble form antibody

Quick Database Links

Gene Symbol

RANK

UniProt

Q9Y6Q6

NCBI Gene ID

8792

RefSeq:001257880, 001270951, 11

Ayantika Kundu 1, Pratiti Ghosh 2, Biswadev Bishayi Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3 Int Immunopharmacol, (2024)

PubMed: 38678669

Applications

WB

Reactivity

Mouse

Sahin Sultana, Rajen Dey, Biswadev Bishayi Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking Immunologic Research, 66, 97 (2018)

PubMed: 29218573

Applications

WB

Reactivity

Mouse

Gopinath Mukherjee 1, Sharmistha Samanta 1, Biswadev Bishayi TLR-4Ab and IFNγAb with exogenous IL-10 treated LPS induced mice shown differential inflammatory response upon RANKL-M-CSF stimulation in Resident Bone Marrow Cells Microb Pathog, (2025)

PubMed: 40023455

Applications

WB

Reactivity

Mouse

Ghosh, Rituparna et al. Simultaneous neutralization of TGF-? and IL-6 attenuates Staphylococcus aureus-induced arthritic inflammation through differential modulation of splenic and synovial macrophages Scand J Immunol, e13252 (2023)

PubMed: 36597222

Applications

WB

Reactivity

Mouse

Murray, Jonathan B. et al. Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts Sci Rep, 11, 9214 (2021)

PubMed: 33911158

Applications

WB

Reactivity

Mouse