RANK antibody

• Catalog Number: orb6560
• Category: Antibodies
• Description: RANK antibody
• Target: RANK
• Clonality: Polyclonal
• Species/Host: Rabbit
• Isotype: IgG
• Conjugation: Unconjugated
• Reactivity: Human, Mouse, Rat
• Form/Appearance: 10 mM PBS, 0.02% sodium azide
• Concentration: - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
• Purity: Purified by Protein A affinity chromatography.
• Immunogen: KLH conjugated synthetic peptide derived from human RANK. Please contact us for the exact immunogen sequence. The peptide is available as orb393922.
• UniProt ID: Q9Y6Q6
• RRID: AB_10926256
• MW: 130kDa
• Tested applications: IHC-P
• Dilution range: IHC-P: 1:100-1:500
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti CD254 antibody, anti hRANKL2 antibody, anti O
• Note: For research use only
• Entrez: 8792
• NCBI: 001270951, 001257880, 11
• Expiration Date: 12 months from date of receipt.

References

Ayantika Kundu 1, Pratiti Ghosh 2, Biswadev Bishayi Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3 Int Immunopharmacol, (2024)

PubMed: 38678669

Applications

WB

Reactivity

Mouse

Gopinath Mukherjee 1, Sharmistha Samanta 1, Biswadev Bishayi TLR-4Ab and IFNγAb with exogenous IL-10 treated LPS induced mice shown differential inflammatory response upon RANKL-M-CSF stimulation in Resident Bone Marrow Cells Microb Pathog, (2025)

PubMed: 40023455

Applications

WB

Reactivity

Mouse

Ghosh, Rituparna et al. Simultaneous neutralization of TGF-? and IL-6 attenuates Staphylococcus aureus-induced arthritic inflammation through differential modulation of splenic and synovial macrophages Scand J Immunol, e13252 (2023)

PubMed: 36597222

Applications

WB

Reactivity

Mouse

Murray, Jonathan B. et al. Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts Sci Rep, 11, 9214 (2021)

PubMed: 33911158

Applications

WB

Reactivity

Mouse

IHC-P staining of human breast cancer tissue using RANK antibody (2.5ug/ml)

Immunohistochemical staining of paraffin embedded rat colon tissue using RANK antibody (2.5ug/ml)

Immunohistochemical staining of paraffin embedded rat pituitary tissue using anti-RANK (2.5ug/ml)

IHC-P image of rat pituitary tissue using anti-RANK (2.5ug/ml)