Rabbit IRF8 Antibody

SKU: orb1523736

Description

IRF8 Antibody

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: ChIP, IP
• Dilution Range: WB - Not recommended; IP - 2 - 10 µg/mg lysate
• Reactivity: Mouse
• Application Notes:
  Format: Whole IgG

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Between 225 and 275
• Target: IRF8
• Purification: Antigen Affinity Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: 2 - 8°C
• Form/Appearance: Liquid
• Buffer/Preservatives: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
• Concentration: 1000 µg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AI893568; ICSBP; Icsbp1; interferon consensus sequence binding protein 1; interferon consensus sequence-binding protein; interferon regulatory factor 8; IRF-8; Myls

Detection of mouse IRF8 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 mg for IP, 20% of IP loaded) from RAW 264.7 cells. Antibodies: Affinity purified rabbit anti-IRF8 antibody orb1523736 used for IP at 6 µg/mg lysate.

Localization of IRF8 binding sites by ChIP-Sequencing. Chromatin from mouse bone marrow dendritic cells (BMDCs) was immunoprecipitated with anti-IRF8 orb1523736 and analyzed by DNA sequencing methods. The figure illustrates the peak distribution of IRF8 binding within a 156 kb region of chromosome 19 (blue) as detected by anti-IRF8 orb1523736.

Quick Database Links

Gene Symbol

IRF8

UniProt

P23611

RefSeq (Protein):NP_032346.1