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PROTAC EGFR degrader 2

SKU: orb1983028

Description

PROTAC EGFR degrader 2 is a highly potent bifunctional molecule with an antiproliferative IC50 of 4.0 nM and induces EGFR degradation with a DC50 of 36.51 nM. Its adaptable linker makes it a valuable chemical tool for constructing NTR-responsive PROTACs, enabling targeted protein degradation research in both cellular and animal models of cancer.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW1151.78
FormulaC58H72ClFN12O8S
TargetEGFR,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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PROTAC EGFR degrader 2 (orb1983028)

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