PROTAC EGFR degrader 17

SKU: orb3177178

Description

PROTACEGFRdegrader 17 (Compound 35) is an EGFR PROTAC degrader with a DC50 value of 0.49 nM. It facilitates the ubiquitination and degradation of EGFR and can be used for research in various cancers, including non-small cell lung cancer.

Key Properties

• CAS Number: 3065209-64-2
• MW: 837.99
• Formula: C₄₆H₅₁N₁₁O₅
• SMILES: O=C1\N=C/2\N(C=3C(N2)=CC=C(C3)N4CCN(CC5CN(C5)C=6C=C7C(=CC6)C(=O)N(C7)C8C(=O)NC(=O)CC8)CC4)C[C@]9(C[C@](CC9)(COC%10=C(C%11=CC1=CC(C)=N%11)C=NN%10C)[H])[H]
• Target: Ligands for E3 Ligase,EGFR,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ligands for E3 Ligase,EGFR,PROTACs