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PPARγ modulator-1

SKU: orb2567005

Description

Anticancer agent 183 (example 48) is a high-affinity, non-agonistic PPARγ modulator that blocks its kinase-mediated phosphorylation. This research compound is used in metabolic disease studies to investigate mechanisms with reduced side-effect profiles, applicable in both cellular and animal models of insulin resistance and diabetes.

Research Area

Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number1415321-54-8
MW540.69
FormulaC34H40N2O4
SMILESC(N1C=2C(=CC(C(N[C@@H](C)C3=CC=C(C(C)(C)C)C=C3)=O)=CC2)C(C)=C1C)C4=CC(OC(C(O)=O)(C)C)=CC=C4
TargetPPAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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PPARγ modulator-1 (orb2567005)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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