(E/Z)-ABP/PPAR modulator 1

SKU: orb3173493

Description

ABP/PPAR modulator 1 is an orally active modulator targeting FABP and PPAR, with IC50 values of 0.65 μM and 1.08 μM for FABP1 and FABP4, respectively, and EC50 values of 9.19 μM, 2.20 μM, and 1.58 μM for PPARα, PPARγ, and PPARδ, respectively. It demonstrates potent anti-metabolic dysfunction-associated steatohepatitis (MASH) activity. ABP/PPAR modulator 1 dose-dependently improves various pathological features of fatty liver in a WD + Carbon tetrachloride-induced MASH mouse model.

Images & Validation

−

Key Properties

−

Target	PPAR,FABP

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

PPAR,FABP

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols