Phospho-alpha Synuclein (Ser129) Antibody

• Catalog Number: orb1730621
• Category: Antibodies
• Description: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Synthetic peptide of human SNCA
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 14 kDa; Observed MW: 18 kDa
• Entrez: 6622
• UniProt ID: P37840
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta com
• Note: For research use only
• Expiration Date: 12 months from date of receipt.