PGR/PR Antibody

• Catalog Number: orb27805
• Category: Antibodies
• Description: Mouse monoclonal antibody to PGR belongs to the nuclear hormone receptor family. It is an intracellular steroid receptor, which specially binds progesterone in humans. The proteins function as dimeric molecules in nuclei, which regulates the transcription of target genes in a ligand-responsive method. It involved in the regulation of eukaryotic gene expression, affect cellular proliferation and differentiation in target tissues.
• Target: PGR
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgM,k
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
• Immunogen: Synthetic Peptide
• UniProt ID: P06401
• MW: 98981
• Tested applications: WB
• Dilution range: WB: 1:100
• Antibody Type: Primary Antibody
• Clone Number: 312CT8.2.1.6
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: Anti-Progesterone receptor antibody, anti-PGR anti
• Research Area: Cancer Biology, Cell Biology, Neuroscience, Signal
• Note: For research use only
• NCBI: NP_000917.3, NP_001258091.1, NP_001189403.1
• Expiration Date: 12 months from date of receipt.

PGR/PR Antibody western blot analysis in SK-BR-3 cell line lysates (35 μg/lane). This demonstrates the PGR/PR antibody detected the PGR/PR protein (arrow).