PGR/PR Antibody

SKU: orb27805

Description

Mouse monoclonal antibody to PGR belongs to the nuclear hormone receptor family. It is an intracellular steroid receptor, which specially binds progesterone in humans. The proteins function as dimeric molecules in nuclei, which regulates the transcription of target genes in a ligand-responsive method. It involved in the regulation of eukaryotic gene expression, affect cellular proliferation and differentiation in target tissues.

Research Area

Cancer Biology, Cell Biology, Neuroscience, Signal Transduction

Images & Validation

• Tested Applications: WB
• Dilution Range: WB - 1:100
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgM,k
• Clone No.: B534EV0X4X3X8
• Immunogen: Synthetic Peptide
• Target: PGR
• Molecular Weight: 98981
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Progesterone receptor antibody, anti-PGR antibody, anti-NR3C3 antibody

Quick Database Links

Gene Symbol

PGR

UniProt

P06401

RefSeq (Protein):NP_000917.3, NP_001258091.1, NP_001189403.1