PF 429242

• Catalog Number: orb1302957
• Category: Small Molecules
• Description: PF 429242
• CAS Number: 947303-87-9
• Purity: 99.27%
• MW: 409.56
• SMILES: N(C(=O)C1=CC=C(CN(CC)CC)C=C1)(CCC2=C(OC)C=CC=C2)[C@@H]3CCNC3
• Formula: C₂₅H₃₅N₃O₂·2HCl
• Biological Activity: PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.