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Perifosine

SKU: orb1226084

Description

A oral bioavailable alkylphospholipid that displays significant antiproliferative activity in vitro and in vivo in several human tumor model; acts as an Akt inhibitor and a PI3K inhibitor, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway; enhances apoptosis and inhibits the growth of xenografts in nude mice combined with a lysosomal inhibitor.Brain Cancer Phase 2 Clinical.

Images & Validation

Key Properties

CAS Number157716-52-4
MW461.6584
Purity>98% (HPLC)
FormulaC25H52NO4P
SMILESO=P(OC1CC[N+](C)(C)CC1)([O-])OCCCCCCCCCCCCCCCCCC
TargetAkt
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

KRX-0401 | NSC 639966 | D-21266 | KRX 0401 | KRX0401 | D21266 | D 21266

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Perifosine (orb1226084)

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Available Sizes

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200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 110.00
10 mg
$ 130.00
25 mg
$ 220.00
50 mg
$ 380.00
100 mg
$ 580.00